what is the dispossable counting chamber slide difference for human clinical ivf sperm analysis and animal breeding reproductive sperm analysis

The primary differences between disposable counting chamber slides for human clinical IVF sperm analysis and animal breeding reproductive sperm analysis involve the design specifications, calibration requirements, and compatibility tailored to their respective applications.

Key Differences

1. Calibration Precision:

   • Human Clinical IVF:
     • Designed with stringent accuracy standards to meet clinical and medical regulations.
     • Chamber depth is carefully calibrated (e.g., 10 µm or 20 µm) to ensure precise analysis of sperm count, motility, and morphology, which directly influence fertility outcomes.
   • Animal Breeding:
     • While precision is still important, the calibration standards are less stringent since animal breeding tolerates broader variations in semen parameters due to species-specific factors.

2. Material Composition:

   • Human Clinical IVF:
     • Made from high-grade medical materials, often glass or high-clarity plastic, to provide optimal visualization under CASA systems.
     • Must comply with medical safety standards like ISO, CE, or FDA approvals.
   • Animal Breeding:
     • Often constructed from durable, cost-effective materials suitable for large-scale use in farming operations.

3. Chamber Design:

   • Human Clinical IVF:
     • Typically has a shallower depth (e.g., 10 µm or 20 µm) for human sperm to enable precise motility and morphology analysis.
     • Special coatings may be used to prevent sperm adherence and ensure uniform sample distribution.
   • Animal Breeding:
     • Chambers might be deeper (e.g., 20 µm or 50 µm) to accommodate the larger sizes and higher concentrations of animal sperm, such as in bulls, boars, or stallions.

4. Species-Specific Adaptations:

   • Animal CASA systems often need slides designed for higher sperm densities or specific motility patterns unique to species like boars, bulls, stallions, or goats.
   • Clinical slides for human IVF are optimized for human sperm behavior and density.

5. Cost Considerations:

   • Human Clinical IVF: Higher costs due to stringent standards and lower sample volumes.
   • Animal Breeding: More cost-effective, with designs that allow for high-throughput usage.

Compatibility with CASA Systems

Both slides are designed to work with CASA (Computer Assisted Sperm Analysis) systems, but their software algorithms and analysis parameters are species-specific:

• Human Clinical CASA: E.g., Hamilton Thorne IVOS III, CEROS II, or other medical-grade systems.
• Animal CASA: E.g., Minitube AndroVision, IMV Technologies systems, or others tailored to veterinary use.

While both types of disposable counting chamber slides serve to improve the accuracy and efficiency of sperm analysis, their differences are driven by the unique demands of human clinical settings versus animal breeding operations. When choosing slides, it is critical to match them to the species and the CASA system used for the analysis.

In China,Our ASCEN CASA disposable counting chamber slide is perfectly match with the world popular CASA Software system for automatic semen analysis.


1. Hamilton Thorne Computer Assisted Sperm Analysis
CASA (Computer Assisted Sperm Analysis) image analysis systems are designed to bring quality, efficiency, and reliability to studies of reproductive cells in the human fertility*, animal sciences, and reproductive toxicology fields. Our sperm analyzers assist researchers and clinicians in analyzing sperm motility, morphology, or other characteristics in human fertility, toxicology, research, and animal applications. IVOS II CASA Sperm Analyzer, CEROS II Microscope Sperm Analyzer, TOX IVOS II CASA Semen Analyzer

2. MICROPTIC CASA Systems SCA CASA System for semen analysis allows the accurate, repetitive and automatic assessment of the following sperm parameters: motility, concentration, morphology, DNA fragmentation, vitality, acrosome reaction and leukocytes.

3. Minitube AndroVision: CASA software with PC and monitor
Androscope AndroVision CASA Analyzer is a highly precise automated system for computerized semen analysis. It not only provides classical analyses of motility, concentration and morphology, but also various fluorescence based assessments of sperm functionality. The basic system for the analysis of motility and concentration is complemented by optional software modules.

4. computer assisted semen analysis System - IMV TECHNOLOGIES
All these CASA Comptuter Assisted Semen Analysis Software System Analyzer popular in the market